The Drug Interaction Database part of UW Drug Interaction Solutions, was developed in the Department of Pharmaceutics, School of Pharmacy at the University of Washington and is designed to support research and regulatory scientists in their decision-making when evaluating PK-based drug interactions and drug safety.
The Drug Interaction Database displays highly detailed preclinical (in vitro, human) and clinical datasets with quantitative and qualitative information related to various intrinsic and extrinsic factors. These factors include interacting co-medications, excipients, food products, herbals, tobacco, organ impairment and genetics, that can affect drug exposure in humans.
The information is extracted from relevant publications and recent NDA/BLA reviews and common metrics (e.g., changes of drug exposure, oral clearance) for active compounds are used across all studies to allow metadata analysis of quantitative results.
The database is web-based and is updated daily by research scientists, experts in drug interactions, and members of the UW Drug Interaction Solutions team.
For more information: http://www.druginteractionsolutions.org
UW Drug Interaction Database is one of the many software programs and tools created at the University of Washington available through our Express Licensing Program. These agreements have standard terms and conditions that allow for rapid licensing by companies, organizations, or individuals.
Download the license (PDF file), sign it, and return it to the UW CoMotion. The conditions and financial terms of this license apply only to those who sign and return it "as is." Some Express Licenses may be modified for an additional cost.
This license is suitable for pharmaceutical companies of all sizes, and most service providers operating in the therapeutics space (preclinical and clinical CROs, CDMOs, and consulting firms). Download the license (PDF file), sign it, and return it to the UW CoMotion. The conditions and financial terms of this license apply only to those who sign and return it "as is." Some Express Licenses may be modified for an additional cost.
For licenses to service providers which offer services other than those referred to above (specialty services such as software modeling tools) please contact UW CoMotion (contact details below) to evaluate conditions and financial terms.